Rapid evaluation and screening of interfacial reactions on self-assembled monolayers.

Three-Component Reaction Discovery Enabled by Mass Spectrometry of Self-Assembled Monolayers

Multicomponent reactions are employed extensively in many areas of organic chemistry. Despite significant progress, the discovery of such enabling transformations remains challenging. Here, we present the development of a parallel, label-free reaction-discovery platform that can be used in the identification of new multicomponent transformations. Our approach is based on parallel mass spectrome...

Fluorinated self-assembled monolayers: composition, structure and interfacial properties

Over the past several years, various fluorinated self-assembled monolayers (F-SAMs) on gold have been used to study the interfacial properties of fluorocarbon interfaces. This review focuses on the structures of selected F-SAMs and describes how the structures relate to various interfacial properties, such as wettability, friction, X-ray induced damage and ion-surface collisions. 2003 Elsevier ...

Determination of kinetic parameters for interfacial enzymatic reactions on self-assembled monolayers.

This paper reports a method to characterize the kinetic constants for the action of enzymes on immobilized substrates. This example uses cutinase, a serine esterase that hydrolyzes 4-hydroxyphenyl valerate moieties that are immobilized on a self-assembled monolayer of alkanethiolates on gold. The product of the enzyme reaction is a hydroquinone, which is redox active and therefore permits the u...

Study on the barrier properties and interfacial properties of self-assembled monolayers (SAMs) of aliphatic, aromatic and alkoxycyanobiphenyl thiols on gold surface prepared using a lyotropic liquid crystalline phase as an adsorbing medium

Orthogonal self-assembled monolayers: alkanethiols on gold and alkane carboxylic acids on alumina.

This work demonstrates the practicality of forming two self-assembled monolayers (SAMs), independently but simultaneously, by adsorption of two different adsorbates from a common solution onto a substrate exposing two different materials at its surface. The experimental procedure and the degree of independence achieved in the resulting SAMs are illustrated by examination of monolayers obtained ...